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Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3532946

Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

About this item

Full title

Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

Publisher

Waltham, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2012-10, Vol.367 (17), p.1596-1606

Language

English

Formats

Publication information

Publisher

Waltham, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

In this study, mortality from colorectal cancer was reduced by about 80% in a subgroup of patients with tumors that expressed a mutated, activated form of phosphatidylinositol 3-kinase (17% of all tumors) when the patients took aspirin regularly after the diagnosis.
Numerous observational and randomized, controlled studies have suggested a prote...

Alternative Titles

Full title

Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3532946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3532946

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1207756

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