Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung can...
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
About this item
Full title
Author / Creator
Rudin, Charles M , Durinck, Steffen , Stawiski, Eric W , Poirier, John T , Modrusan, Zora , Shames, David S , Bergbower, Emily A , Guan, Yinghui , Shin, James , Guillory, Joseph , Rivers, Celina Sanchez , Foo, Catherine K , Bhatt, Deepali , Stinson, Jeremy , Gnad, Florian , Haverty, Peter M , Gentleman, Robert , Chaudhuri, Subhra , Janakiraman, Vasantharajan , Jaiswal, Bijay S , Parikh, Chaitali , Yuan, Wenlin , Zhang, Zemin , Koeppen, Hartmut , Wu, Thomas D , Stern, Howard M , Yauch, Robert L , Huffman, Kenneth E , Paskulin, Diego D , Illei, Peter B , Varella-Garcia, Marileila , Gazdar, Adi F , de Sauvage, Frederic J , Bourgon, Richard , Minna, John D , Brock, Malcolm V and Seshagiri, Somasekar
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Sekar Seshagiri and colleagues report exome, transcriptome and copy-number alteration data in small-cell lung cancer. The authors find
SOX2
amplification in 27% of samples and also identify a recurrent
RFL
-
MYCL1
fusion.
Small-cell lung cancer (SCLC) is an exceptionally aggressive disease with poor prognosis. Here, we obtained...
Alternative Titles
Full title
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
Authors, Artists and Contributors
Author / Creator
Durinck, Steffen
Stawiski, Eric W
Poirier, John T
Modrusan, Zora
Shames, David S
Bergbower, Emily A
Guan, Yinghui
Shin, James
Guillory, Joseph
Rivers, Celina Sanchez
Foo, Catherine K
Bhatt, Deepali
Stinson, Jeremy
Gnad, Florian
Haverty, Peter M
Gentleman, Robert
Chaudhuri, Subhra
Janakiraman, Vasantharajan
Jaiswal, Bijay S
Parikh, Chaitali
Yuan, Wenlin
Zhang, Zemin
Koeppen, Hartmut
Wu, Thomas D
Stern, Howard M
Yauch, Robert L
Huffman, Kenneth E
Paskulin, Diego D
Illei, Peter B
Varella-Garcia, Marileila
Gazdar, Adi F
de Sauvage, Frederic J
Bourgon, Richard
Minna, John D
Brock, Malcolm V
Seshagiri, Somasekar
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3557461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3557461
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2405
