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MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3582131

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

About this item

Full title

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-03, Vol.123 (3), p.1176-1181

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Milk fat globule-EGF 8 (MFGE8) plays important, nonredundant roles in several biological processes, including apoptotic cell clearance, angiogenesis, and adaptive immunity. Several recent studies have reported a potential role for MFGE8 in regulation of the innate immune response; however, the precise mechanisms underlying this role are poorly unde...

Alternative Titles

Full title

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3582131

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3582131

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI65167

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