Naive pluripotency is associated with global DNA hypomethylation
Naive pluripotency is associated with global DNA hypomethylation
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Naive pluripotent embryonic stem cells (ESCs) and embryonic germ cells (EGCs) have distinct developmental origins. Genome-wide expression and global DNA-methylation analyses now reveal that ESCs and ESGs are highly similar at the transcriptome level and, contrary to previous assumptions, are both characterized by DNA hypomethylation. Also, global m...
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Full title
Naive pluripotency is associated with global DNA hypomethylation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3591483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3591483
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2510
