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Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3616391

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

About this item

Full title

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6077), p.91-95

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Endogenous thymic regeneration is a crucial function that allows for renewal of immune competence after stress, infection, or immunodepletion. However, the mechanisms governing this regeneration remain poorly understood. We detail such a mechanism, centered on interleukin-22 (IL-22) and triggered by the depletion of CD4⁺CD8⁺ double-positive thymocy...

Alternative Titles

Full title

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3616391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3616391

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1218004

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