A High-Coverage Genome Sequence from an Archaic Denisovan Individual
A High-Coverage Genome Sequence from an Archaic Denisovan Individual
About this item
Full title
Author / Creator
Meyer, Matthias , Kircher, Martin , Gansauge, Marie-Theres , Li, Heng , Racimo, Fernando , Mallick, Swapan , Schraiber, Joshua G. , Jay, Flora , Prüfer, Kay , de Filippo, Cesare , Sudmant, Peter H. , Alkan, Can , Fu, Qiaomei , Do, Ron , Rohland, Nadin , Tandon, Arti , Siebauer, Michael , Green, Richard E. , Bryc, Katarzyna , Briggs, Adrian W. , Stenzel, Udo , Dabney, Jesse , Shendure, Jay , Kitzman, Jacob , Hammer, Michael F. , Shunkov, Michael V. , Derevianko, Anatoli P. , Patterson, Nick , Andrés, Aida M. , Eichler, Evan E. , Slatkin, Montgomery , Reich, David , Kelso, Janet and Pääbo, Svante
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
We present a DNA library preparation method that has allowed us to reconstruct a high-coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The quality of this genome allows a direct estimation of Denisovan heterozygosity indicating that genetic diversity in these archaic hominins was extremely low. It also allows tenta...
Alternative Titles
Full title
A High-Coverage Genome Sequence from an Archaic Denisovan Individual
Authors, Artists and Contributors
Author / Creator
Kircher, Martin
Gansauge, Marie-Theres
Li, Heng
Racimo, Fernando
Mallick, Swapan
Schraiber, Joshua G.
Jay, Flora
Prüfer, Kay
de Filippo, Cesare
Sudmant, Peter H.
Alkan, Can
Fu, Qiaomei
Do, Ron
Rohland, Nadin
Tandon, Arti
Siebauer, Michael
Green, Richard E.
Bryc, Katarzyna
Briggs, Adrian W.
Stenzel, Udo
Dabney, Jesse
Shendure, Jay
Kitzman, Jacob
Hammer, Michael F.
Shunkov, Michael V.
Derevianko, Anatoli P.
Patterson, Nick
Andrés, Aida M.
Eichler, Evan E.
Slatkin, Montgomery
Reich, David
Kelso, Janet
Pääbo, Svante
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3617501
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3617501
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1224344
