Sulfhydration mediates neuroprotective actions of parkin
Sulfhydration mediates neuroprotective actions of parkin
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Increases in S-nitrosylation and inactivation of the neuroprotective ubiquitin E3 ligase, parkin, in the brains of patients with Parkinson’s disease are thought to be pathogenic and suggest a possible mechanism linking parkin to sporadic Parkinson’s disease. Here we demonstrate that physiologic modification of parkin by hydrogen sulfide, termed sul...
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Sulfhydration mediates neuroprotective actions of parkin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622945
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622945
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E-ISSN
2041-1723
DOI
10.1038/ncomms2623
