Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclero...
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Oligodendrocytes form myelin sheaths and provide metabolic support to axons. Using
in vivo
genetic fate tracing in a mouse model of amyotrophic lateral sclerosis (ALS), this study shows that there is extensive degeneration of oligodendrocytes near motor neurons prior to behavioral manifestation of disease. Although oligodendrocytes were regen...
Alternative Titles
Full title
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3637847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3637847
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3357
