Landscape of Somatic Retrotransposition in Human Cancers
Landscape of Somatic Retrotransposition in Human Cancers
About this item
Full title
Author / Creator
Lee, Eunjung , Iskow, Rebecca , Yang, Lixing , Gokcumen, Omer , Haseley, Psalm , Luquette, Lovelace J. , Lohr, Jens G. , Harris, Christopher C. , Ding, Li , Wilson, Richard K. , Wheeler, David A. , Gibbs, Richard A. , Kucherlapati, Raju , Lee, Charles , Kharchenko, Peter V. , Park, Peter J. , The Cancer Genome Atlas Research Network and Cancer Genome Atlas Research Network
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Transposable elements (TEs) are abundant in the human genome, and some are capable of generating new insertions through RNA intermediates. In cancer, the disruption of cellular mechanisms that normally suppress TE activity may facilitate mutagenic retrotranspositions. We performed single-nucleotide resolution analysis of TE insertions in 43 high-co...
Alternative Titles
Full title
Landscape of Somatic Retrotransposition in Human Cancers
Authors, Artists and Contributors
Author / Creator
Iskow, Rebecca
Yang, Lixing
Gokcumen, Omer
Haseley, Psalm
Luquette, Lovelace J.
Lohr, Jens G.
Harris, Christopher C.
Ding, Li
Wilson, Richard K.
Wheeler, David A.
Gibbs, Richard A.
Kucherlapati, Raju
Lee, Charles
Kharchenko, Peter V.
Park, Peter J.
The Cancer Genome Atlas Research Network
Cancer Genome Atlas Research Network
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3656569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3656569
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1222077
