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Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3661710

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

About this item

Full title

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2013-06, Vol.9 (6), p.374-382

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Structure-based design of RARα antagonists leads to compounds that can selectively upregulate chaperone-mediated autophagy (CMA), yielding the first chemically tractable target for regulating CMA in cells.
Chaperone-mediated autophagy (CMA) contributes to cellular quality control and the cellular response to stress through the selective degradat...

Alternative Titles

Full title

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3661710

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3661710

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.1230

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