Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visce...
Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visceral leishmaniasis
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Author / Creator
Fakiola, Michaela , Strange, Amy , Cordell, Heather J. , Miller, E. Nancy , Pirinen, Matti , Su, Zhan , Mishra, Anshuman , Mehrotra, Sanjana , Monteiro, Gloria R. , Band, Gavin , Bellenguez, Céline , Dronov, Serge , Edkins, Sarah , Freeman, Colin , Giannoulatou, Eleni , Gray, Emma , Hunt, Sarah E. , Lacerda, Henio G. , Langford, Cordelia , Pearson, Richard , Pontes, Núbia N. , Rai, Madhukar , Singh, S.P. , Smith, Linda , Sousa, Olivia , Vukcevic, Damjan , Bramon, Elvira , Brown, Matthew A. , Casas, Juan P. , Corvin, Aiden , Duncanson, Audrey , Jankowski, Janusz , Markus, Hugh S. , Mathew, Christopher G. , Palmer, Colin N.A. , Plomin, Robert , Rautanen, Anna , Sawcer, Stephen J. , Trembath, Richard C. , Viswanathan, Ananth C. , Wood, Nicholas W. , Wilson, Mary E. , Deloukas, Panos , Peltonen, Leena , Christiansen, Frank , Witt, Campbell , Jeronimo, Selma M.B. , Sundar, Shyam , Spencer, Chris C.A. , Blackwell, Jenefer M. and Donnelly, Peter
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
To identify susceptibility loci for visceral leishmaniasis we undertook genome-wide association studies in two populations; 989 cases and 1089 controls from India, and 357 cases in 308 Brazilian families (1970 individuals). The HLA-DRB1-HLA-DQA1 locus was the only region to show strong evidence of association in both populations. Replication at thi...
Alternative Titles
Full title
Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visceral leishmaniasis
Authors, Artists and Contributors
Author / Creator
Strange, Amy
Cordell, Heather J.
Miller, E. Nancy
Pirinen, Matti
Su, Zhan
Mishra, Anshuman
Mehrotra, Sanjana
Monteiro, Gloria R.
Band, Gavin
Bellenguez, Céline
Dronov, Serge
Edkins, Sarah
Freeman, Colin
Giannoulatou, Eleni
Gray, Emma
Hunt, Sarah E.
Lacerda, Henio G.
Langford, Cordelia
Pearson, Richard
Pontes, Núbia N.
Rai, Madhukar
Singh, S.P.
Smith, Linda
Sousa, Olivia
Vukcevic, Damjan
Bramon, Elvira
Brown, Matthew A.
Casas, Juan P.
Corvin, Aiden
Duncanson, Audrey
Jankowski, Janusz
Markus, Hugh S.
Mathew, Christopher G.
Palmer, Colin N.A.
Plomin, Robert
Rautanen, Anna
Sawcer, Stephen J.
Trembath, Richard C.
Viswanathan, Ananth C.
Wood, Nicholas W.
Wilson, Mary E.
Deloukas, Panos
Peltonen, Leena
Christiansen, Frank
Witt, Campbell
Jeronimo, Selma M.B.
Sundar, Shyam
Spencer, Chris C.A.
Blackwell, Jenefer M.
Donnelly, Peter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3664012
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3664012
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2518