Species-specific impact of the autophagy machinery on Chikungunya virus infection
Species-specific impact of the autophagy machinery on Chikungunya virus infection
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Chikungunya virus (CHIKV) is a recently re‐emerged arbovirus that triggers autophagy. Here, we show that CHIKV interacts with components of the autophagy machinery during its replication cycle, inducing a cytoprotective effect. The autophagy receptor p62 protects cells from death by binding ubiquitinated capsid and targeting it to autophagolysosome...
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Full title
Species-specific impact of the autophagy machinery on Chikungunya virus infection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3674439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3674439
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ISSN
1469-221X
E-ISSN
1469-3178
DOI
10.1038/embor.2013.51
