Deregulations in the Cyclin-Dependent Kinase-9-Related Pathway in Cancer: Implications for Drug Disc...
Deregulations in the Cyclin-Dependent Kinase-9-Related Pathway in Cancer: Implications for Drug Discovery and Development
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Egypt: Hindawi Publishing Corporation
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Language
English
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Egypt: Hindawi Publishing Corporation
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Contents
The CDK9-related pathway is an important regulator of mammalian cell biology and is also involved in the replication cycle of several viruses, including the human immunodeficiency virus type 1. CDK9 is present in two isoforms termed CDK9-42 and CDK9-55 that bind noncovalently type T cyclins and cyclin K. This association forms a heterodimer, where...
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Full title
Deregulations in the Cyclin-Dependent Kinase-9-Related Pathway in Cancer: Implications for Drug Discovery and Development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3690251
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3690251
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ISSN
2090-5661,2090-567X
E-ISSN
2090-567X
DOI
10.1155/2013/305371
