Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
The mammalian circadian clock involves a transcriptional feedback loop in which CLOCK and BMAL1 activate the Period and Cryptochrome genes, which then feed back and repress their own transcription. We have interrogated the transcriptional architecture of the drcadian transcriptional regulatory loop on a genome scale in mouse liver and find a stereo...
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Full title
Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3694775
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3694775
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1226339
