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Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696542

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

About this item

Full title

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.2803-2815

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The skin interstitium sequesters excess Na+ and Cl- in salt-sensitive hypertension. Mononuclear phagocyte system (MPS) cells are recruited to the skin, sense the hypertonic electrolyte accumulation in skin, and activate the tonicity-responsive enhancer-binding protein (TONEBP, also known as NFAT5) to initiate expression and secretion of VEGFC, whic...

Alternative Titles

Full title

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696542

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696542

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI60113

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