In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebell...
In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex
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Publisher
Washington, DC: National Academy of Sciences
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Language
English
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Publisher
Washington, DC: National Academy of Sciences
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Contents
Plasticity in the central nervous system in response to injury is a complex process involving axonal remodeling regulated by specific molecular pathways. Here, we dissected the role of growthassociated protein 43 (GAP-43; also known as neuromodulin and B-50) in axonal structural plasticity by using, as a model, climbing fibers. Single axonal branch...
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Full title
In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696745
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1219256110
