Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers
Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Satellite repeats in heterochromatin are transcribed into noncoding RNAs that have been linked to gene silencing and maintenance of chromosomal integrity. Using digital gene expression analysis, we showed that these transcripts are greatly overexpressed in mouse and human epithelial cancers. In 8 of 10 mouse pancreatic ductal adenocarcinomas (PDACs...
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Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3701432
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3701432
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1200801