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Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3701432

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

About this item

Full title

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2011-02, Vol.331 (6017), p.593-596

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Satellite repeats in heterochromatin are transcribed into noncoding RNAs that have been linked to gene silencing and maintenance of chromosomal integrity. Using digital gene expression analysis, we showed that these transcripts are greatly overexpressed in mouse and human epithelial cancers. In 8 of 10 mouse pancreatic ductal adenocarcinomas (PDACs...

Alternative Titles

Full title

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3701432

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3701432

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1200801

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