CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
About this item
Full title
Author / Creator
Alzheimer Disease Neuroimaging Initiative , The Alzheimer Disease Neuroimaging Initiative , Bradshaw, Elizabeth M , Chibnik, Lori B , Keenan, Brendan T , Ottoboni, Linda , Raj, Towfique , Tang, Anna , Rosenkrantz, Laura L , Imboywa, Selina , Lee, Michelle , Von Korff, Alina , Morris, Martha C , Evans, Denis A , Johnson, Keith , Sperling, Reisa A , Schneider, Julie A , Bennett, David A and De Jager, Philip L
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies have identified
CD33
as an Alzheimer's disease susceptibility locus. Here, the authors show that the
CD33
risk allele is associated with altered myeloid function, microglial activation and
in vivo
amyloid pathology.
In our functional dissection of the
CD33
Alzheimer's disease susceptibility...
Alternative Titles
Full title
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
Authors, Artists and Contributors
Author / Creator
The Alzheimer Disease Neuroimaging Initiative
Bradshaw, Elizabeth M
Chibnik, Lori B
Keenan, Brendan T
Ottoboni, Linda
Raj, Towfique
Tang, Anna
Rosenkrantz, Laura L
Imboywa, Selina
Lee, Michelle
Von Korff, Alina
Morris, Martha C
Evans, Denis A
Johnson, Keith
Sperling, Reisa A
Schneider, Julie A
Bennett, David A
De Jager, Philip L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3703870
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3703870
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3435
