Hemin and Zinc Protoporphyrin IX Affect Granisetron Constipating Effects In Vitro and In Vivo
Hemin and Zinc Protoporphyrin IX Affect Granisetron Constipating Effects In Vitro and In Vivo
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Publisher
Egypt: Hindawi Publishing Corporation
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Language
English
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Publisher
Egypt: Hindawi Publishing Corporation
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Contents
Granisetron is a 5-HT3 receptors antagonist used in the management of emesis associated with anticancer chemotherapy. It affects intestinal motility with constipating effect. Since the pathway heme oxygenase/carbon monoxide (HO/CO) is involved in gastrointestinal motility, we evaluated the possible interplay between granisetron and agents affecting...
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Full title
Hemin and Zinc Protoporphyrin IX Affect Granisetron Constipating Effects In Vitro and In Vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3705784
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3705784
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ISSN
2090-4398,2090-4401
E-ISSN
2090-4401
DOI
10.1155/2013/612037