Three-dimensional reconstruction of protein networks provides insight into human genetic disease
Three-dimensional reconstruction of protein networks provides insight into human genetic disease
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Large-scale structural genomics and genome-wide association studies generate a wealth of data relevant to human disease. Wang
et al
. interpret these data in the context of a protein interaction network, showing that systematic analyses of the structural interfaces hit by mutations yield insights into pathogenesis.
To better understand the...
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Full title
Three-dimensional reconstruction of protein networks provides insight into human genetic disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3708476
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3708476
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2106
