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The nuclear receptor LXRα controls the functional specialization of splenic macrophages

The nuclear receptor LXRα controls the functional specialization of splenic macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3720686

The nuclear receptor LXRα controls the functional specialization of splenic macrophages

About this item

Full title

The nuclear receptor LXRα controls the functional specialization of splenic macrophages

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2013-08, Vol.14 (8), p.831-839

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Liver X receptors (LXRs) are transcription factors that respond to sterols. Castrillo and colleagues identify a unique requirement for LXRα in the development of splenic marginal zone macrophages and their antibody responses to blood-borne antigen.
Macrophages are professional phagocytic cells that orchestrate innate immune responses and have co...

Alternative Titles

Full title

The nuclear receptor LXRα controls the functional specialization of splenic macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3720686

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3720686

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2622

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