BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The polycomb protein BMI1 has been linked to maintenance of adult stem cells. Klein and colleagues find that BMI1 is also required for the maintenance of stem cells in the continuously growing mouse incisor, through repression of the
Ink4a/Arf
locus to modulate the proliferation of stem cells and repression of
Hox
genes to prevent inapp...
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Full title
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3735916
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3735916
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2766
