Telomere dysfunction induces metabolic and mitochondrial compromise
Telomere dysfunction induces metabolic and mitochondrial compromise
About this item
Full title
Author / Creator
Sahin, Ergün , Colla, Simona , Liesa, Marc , Moslehi, Javid , Müller, Florian L. , Guo, Mira , Cooper, Marcus , Kotton, Darrell , Fabian, Attila J. , Walkey, Carl , Maser, Richard S. , Tonon, Giovanni , Foerster, Friedrich , Xiong, Robert , Wang, Y. Alan , Shukla, Sachet A. , Jaskelioff, Mariela , Martin, Eric S. , Heffernan, Timothy P. , Protopopov, Alexei , Ivanova, Elena , Mahoney, John E. , Kost-Alimova, Maria , Perry, Samuel R. , Bronson, Roderick , Liao, Ronglih , Mulligan, Richard , Shirihai, Orian S. , Chin, Lynda and DePinho, Ronald A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis to drive progressive atrophy and functional decline in high-turnover tissues. The broader adverse impact of telomere dysfunction across many tissues including more quiescent systems prompted transcriptomic network analyses to identify common mechanisms oper...
Alternative Titles
Full title
Telomere dysfunction induces metabolic and mitochondrial compromise
Authors, Artists and Contributors
Author / Creator
Colla, Simona
Liesa, Marc
Moslehi, Javid
Müller, Florian L.
Guo, Mira
Cooper, Marcus
Kotton, Darrell
Fabian, Attila J.
Walkey, Carl
Maser, Richard S.
Tonon, Giovanni
Foerster, Friedrich
Xiong, Robert
Wang, Y. Alan
Shukla, Sachet A.
Jaskelioff, Mariela
Martin, Eric S.
Heffernan, Timothy P.
Protopopov, Alexei
Ivanova, Elena
Mahoney, John E.
Kost-Alimova, Maria
Perry, Samuel R.
Bronson, Roderick
Liao, Ronglih
Mulligan, Richard
Shirihai, Orian S.
Chin, Lynda
DePinho, Ronald A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3741661
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3741661
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09787
