Humanized mice for immune system investigation: progress, promise and challenges
Humanized mice for immune system investigation: progress, promise and challenges
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Severely immunodeficient mice engrafted with functional human cells and tissues, known as 'humanized' mice, facilitate progress in studies of human haematopoiesis, immunity, gene therapy, infectious diseases, cancer and regenerative medicine.
Mice homozygous for the severe combined immunodeficiency (
scid
) gene mutation or f...
Alternative Titles
Full title
Humanized mice for immune system investigation: progress, promise and challenges
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3749872
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3749872
Other Identifiers
ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3311
