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Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3754258

Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

About this item

Full title

Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-09, Vol.123 (9), p.3751-3755

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Chronic granulomatous disease (CGD) patients have recurrent life-threatening bacterial and fungal infections. Olfactomedin 4 (OLFM4) is a neutrophil granule protein that negatively regulates host defense against bacterial infection. The goal of this study was to evaluate the impact of Olfm4 deletion on host defense against Staphylococcus aureus and...

Alternative Titles

Full title

Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3754258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3754258

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI68453

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