Comparison of in-vitro and in-vivo response to fetal hemoglobin production and γ-mRNA expression by...
Comparison of in-vitro and in-vivo response to fetal hemoglobin production and γ-mRNA expression by hydroxyurea in Hemoglobinopathies
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India: Medknow Publications
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English
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India: Medknow Publications
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Background: Hydroxyurea, which induces Fetal hemoglobin (HbF) synthesis, is the only drug widely used in different hemoglobinopathies; however, the response is very variable. We compared the efficacy of hydroxyurea in-vitro in erythroid cultures and in-vivo in the same patients with different hemoglobinopathies to induce HbF production and enhance...
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Comparison of in-vitro and in-vivo response to fetal hemoglobin production and γ-mRNA expression by hydroxyurea in Hemoglobinopathies
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3758735
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3758735
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ISSN
0971-6866
E-ISSN
1998-362X
DOI
10.4103/0971-6866.116128
