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Chronic Interferon-α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Associat...

Chronic Interferon-α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Associat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773667

Chronic Interferon-α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Association with Anhedonia-Like Behavior in Nonhuman Primates

About this item

Full title

Chronic Interferon-α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Association with Anhedonia-Like Behavior in Nonhuman Primates

Publisher

Basingstoke: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2013-10, Vol.38 (11), p.2179-2187

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing Group

More information

Scope and Contents

Contents

Neuroimaging studies in humans have demonstrated that inflammatory cytokines target basal ganglia function and presynaptic dopamine (DA), leading to symptoms of depression. Cytokine-treated nonhuman primates also exhibit evidence of altered DA metabolism in association with depressive-like behaviors. To further examine cytokine effects on striatal...

Alternative Titles

Full title

Chronic Interferon-α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Association with Anhedonia-Like Behavior in Nonhuman Primates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773667

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/npp.2013.115

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