The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of...
The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Microglia are thought to play important roles in the maintenance of neuronal circuitry and the regulation of behavior. We found that the cortical microglia contain an intrinsic molecular clock and exhibit a circadian expression of cathepsin S (CatS), a microglia-specific lysosomal cysteine protease in the brain. The genetic deletion of CatS causes...
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Full title
The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3783043
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3783043
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep02744
