Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA
Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA
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Publisher
San Francisco, USA: Public Library of Science
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Language
English
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Publisher
San Francisco, USA: Public Library of Science
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Contents
Viruses that generate capped RNA lacking 2′O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons. We used proteome-wide affinity purification coupled to mass spectrometry to identify human and mouse proteins specifically binding to capped RNA with different methylation states. This analysis, complem...
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Full title
Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3789756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3789756
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003663