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Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3789756

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

About this item

Full title

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

Publisher

San Francisco, USA: Public Library of Science

Journal title

PLoS pathogens, 2013-10, Vol.9 (10), p.e1003663

Language

English

Formats

Publication information

Publisher

San Francisco, USA: Public Library of Science

More information

Scope and Contents

Contents

Viruses that generate capped RNA lacking 2′O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons. We used proteome-wide affinity purification coupled to mass spectrometry to identify human and mouse proteins specifically binding to capped RNA with different methylation states. This analysis, complem...

Alternative Titles

Full title

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3789756

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3789756

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003663

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