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Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3792792

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

About this item

Full title

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2012-06, Vol.18 (6), p.918-925

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Retinoids and their precursors are known to regulate adipose tissue maturation. Jorge Plutzky and his colleagues now show that an increased endogenous level of retinaldehyde in white adipose tissue, generated by genetic deletion of Raldh1, promotes its 'beiging' in a retinoic acid receptor–dependent manner. They also showed that genetic knockdown o...

Alternative Titles

Full title

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3792792

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3792792

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.2757

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