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WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3801434

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

About this item

Full title

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2013-10, Vol.32 (20), p.2685-2696

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Autophagy degrades cytoplasmic proteins and organelles to recycle cellular components that are required for cell survival and tissue homeostasis. However, it is not clear how autophagy is regulated in mammalian cells. WASH (Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue) plays an essential role in endosomal sorting through facilitating...

Alternative Titles

Full title

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3801434

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3801434

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2013.189

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