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Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3804158

Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

About this item

Full title

Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

Publisher

United States: Elsevier Inc

Journal title

Neuron (Cambridge, Mass.), 2013-07, Vol.79 (2), p.241-253

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Optogenetic techniques provide effective ways of manipulating the functions of selected neurons with light. In the current study, we engineered an optogenetic technique that directly inhibits neurotransmitter release. We used a genetically encoded singlet oxygen generator, miniSOG, to conduct chromophore assisted light inactivation (CALI) of synapt...

Alternative Titles

Full title

Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3804158

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3804158

Other Identifiers

ISSN

0896-6273

E-ISSN

1097-4199

DOI

10.1016/j.neuron.2013.05.022

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