Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Detailed analyses of siRNA delivery by lipid nanoparticles reveal major pathways of siRNA internalization and endosomal escape.
Despite efforts to understand the interactions between nanoparticles and cells, the cellular processes that determine the efficiency of intracellular drug delivery remain unclear. Here we examine cellular uptake of shor...
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Full title
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3814166
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3814166
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2614
