Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and path...
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
About this item
Full title
Author / Creator
Guichard, Cécile , Amaddeo, Giuliana , Imbeaud, Sandrine , Ladeiro, Yannick , Pelletier, Laura , Maad, Ichrafe Ben , Calderaro, Julien , Bioulac-Sage, Paulette , Letexier, Mélanie , Degos, Françoise , Clément, Bruno , Balabaud, Charles , Chevet, Eric , Laurent, Alexis , Couchy, Gabrielle , Letouzé, Eric , Calvo, Fabien and Zucman-Rossi, Jessica
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Jessica Zucman-Rossi and colleagues report exome sequencing of 24 hepatocellular carcinomas and non-tumor liver tissues and copy-number analysis of 125 tumors. They identify new recurrent mutations in
ARID1A
,
RPS6KA3
,
NFE2L2
and
IRF2
in HCC.
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Her...
Alternative Titles
Full title
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Amaddeo, Giuliana
Imbeaud, Sandrine
Ladeiro, Yannick
Pelletier, Laura
Maad, Ichrafe Ben
Calderaro, Julien
Bioulac-Sage, Paulette
Letexier, Mélanie
Degos, Françoise
Clément, Bruno
Balabaud, Charles
Chevet, Eric
Laurent, Alexis
Couchy, Gabrielle
Letouzé, Eric
Calvo, Fabien
Zucman-Rossi, Jessica
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3819251
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3819251
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2256
