Chromatin marks identify critical cell types for fine mapping complex trait variants
Chromatin marks identify critical cell types for fine mapping complex trait variants
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Soumya Raychaudhuri and colleagues report a broadly applicable method that uses chromatin marks, specifically H3K4me3, to identify critical cell types to fine map complex trait variants.
If trait-associated variants alter regulatory regions, then they should fall within chromatin marks in relevant cell types. However, it is unclear which of the...
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Full title
Chromatin marks identify critical cell types for fine mapping complex trait variants
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3826950
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3826950
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2504
