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Distinct H3F3A and H3F3B driver variants define chondroblastoma and giant cell tumour of bone

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Distinct H3F3A and H3F3B driver variants define chondroblastoma and giant cell tumour of bone

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839851

Distinct H3F3A and H3F3B driver variants define chondroblastoma and giant cell tumour of bone

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Contents

It is recognised that some mutated cancer genes contribute to the development of many cancer types whilst others are cancer-type specific. Amongst genes that affect multiple cancer classes, mutations are usually similar in the different cancer types. Here, however, we observed exquisite tumour-type specificity of different histone 3.3 driver mutati...

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Full title

Distinct H3F3A and H3F3B driver variants define chondroblastoma and giant cell tumour of bone

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839851

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ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2814

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