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An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3843506

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

About this item

Full title

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2013-01, Vol.339 (6118), p.464-467

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Mitochondrial fission is fundamentally important to cellular physiology. The dynamin-related protein Drp1 mediates fission, and interaction between mitochondrion and endoplasmic reticulum (ER) enhances fission. However, the mechanism for Drp1 recruitment to mitochondria is unclear, although previous results implicate actin involvement. Here, we fou...

Alternative Titles

Full title

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3843506

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3843506

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1228360

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