Establishment of totipotency does not depend on Oct4A
Establishment of totipotency does not depend on Oct4A
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oct4 is a core component of the regulatory network of pluripotency. Schöler and colleagues found that establishment of totipotency was not affected by genetic elimination of maternal Oct4a, with live offspring being born and oocytes able to reprogram somatic cell nuclei. However, ablation of both maternal and zygotic Oct4a led to the formation of a...
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Full title
Establishment of totipotency does not depend on Oct4A
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3845671
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3845671
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2816
