Completion of the entire hepatitis C virus life cycle in genetically humanized mice
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The entire hepatitis C virus life cycle can be recapitulated in an inbred mouse model, allowing preclinical assessment of antiviral therapeutics and vaccines.
Humanized mouse model for hepatitis C infection
In a 2009
Nature
paper, Alexander Ploss and colleagues showed that transient expression of the human genes
CD81
and occludin...
Alternative Titles
Full title
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3858853
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3858853
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12427
