Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, an...
Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Contents
RNA-seq is now widely used to quantitatively assess gene expression, expression differences and isoform switching, and promises to deliver results for the entire transcriptome. However, whether the transcriptional state of a gene can be captured accurately depends critically on library preparation, read alignment, expression estimation and the test...
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Full title
Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3879183
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3879183
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/1471-2105-14-370