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ArticlesPeer ReviewedFull Text
Long fragments achieve lower base quality in Illumina paired-end sequencing
Author / Creator:Tan, Ge ; Opitz, Lennart ; Schlapbach, Ralph ; Rehrauer, Hubert
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-02, Vol.9 (1), p.2856-2856, Article 2856
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Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs
Author / Creator:Sarker, Gitalee ; Sun, Wenfei ; Rosenkranz, David ; Pelczar, Pawel ; Opitz, Lennart ; Efthymiou, Vissarion ; Wolfrum, Christian ; Peleg-Raibstein, Daria
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (21), p.10547-10556
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SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis
Author / Creator:Hatakeyama, Masaomi ; Opitz, Lennart ; Russo, Giancarlo ; Qi, Weihong ; Schlapbach, Ralph ; Rehrauer, Hubert
Publisher:England: BioMed Central
Journal title:BMC bioinformatics, 2016-06, Vol.17 (1), p.228-228, Article 228
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A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspring
Author / Creator:Scarborough, Joseph ; Mueller, Flavia S. ; Weber-Stadlbauer, Ulrike ; Mattei, Daniele ; Opitz, Lennart ; Cattaneo, Annamaria ; Richetto, Juliet
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-11, Vol.26 (11), p.6756-6772
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ArticlesPeer ReviewedFull Text
SRF and MKL1 Independently Inhibit Brown Adipogenesis
Author / Creator:Rosenwald, Matthias ; Efthymiou, Vissarion ; Opitz, Lennart ; Wolfrum, Christian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-01, Vol.12 (1), p.e0170643-e0170643
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Impact of RNA degradation on gene expression profiling
Author / Creator:Opitz, Lennart ; Salinas-Riester, Gabriela ; Grade, Marian ; Jung, Klaus ; Jo, Peter ; Emons, Georg ; Ghadimi, B Michael ; Beißbarth, Tim ; Gaedcke, Jochen
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2010-08, Vol.3 (1), p.36-36, Article 36
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Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring
Author / Creator:Sun, Wenfei ; Dong, Hua ; Becker, Anton S. ; Dapito, Dianne H. ; Modica, Salvatore ; Grandl, Gerald ; Opitz, Lennart ; Efthymiou, Vissarion ; Straub, Leon G. ; Sarker, Gitalee ; Balaz, Miroslav ; Balazova, Lucia ; Perdikari, Aliki ; Kiehlmann, Elke ; Bacanovic, Sara ; Zellweger, Caroline ; Peleg-Raibstein, Daria ; Pelczar, Pawel ; Reik, Wolf ; Burger, Irene A. ; von Meyenn, Ferdinand ; Wolfrum, Christian
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-09, Vol.24 (9), p.1372-1383
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ArticlesPeer ReviewedFull Text
Engineered peptide barcodes for in-depth analyses of binding protein libraries
Author / Creator:Egloff, Pascal ; Zimmermann, Iwan ; Arnold, Fabian M. ; Hutter, Cedric A. J. ; Morger, Damien ; Opitz, Lennart ; Poveda, Lucy ; Keserue, Hans-Anton ; Panse, Christian ; Roschitzki, Bernd ; Seeger, Markus A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2019-05, Vol.16 (5), p.421-428
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The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers
Author / Creator:Zajac, Natalia ; Vlachos, Ioannis S ; Sajibu, Sija ; Opitz, Lennart ; Wang, Shuoshuo ; Chittur, Sridar V ; Mason, Christopher E ; Knudtson, Kevin L ; Ashton, John M ; Rehrauer, Hubert ; Aquino, Catharine
Publisher:England: BioMed Central
Journal title:Genome Biology, 2025-05, Vol.26 (1), p.145-17
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Identification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women
Author / Creator:Pérez Vertti Valdés, Melina ; Jüngel, Astrid ; Bitterli, Pamela ; Devan, Jan ; Rehrauer, Hubert ; Opitz, Lennart ; Sirucek, Laura ; Schweinhardt, Petra ; Catanzaro, Sabrina ; Distler, Oliver ; Brunner, Florian ; Dudli, Stefan
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2025-03, Vol.31 (1), p.94-17, Article 94
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ArticlesPeer ReviewedFull Text
Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
Author / Creator:Rehrauer, Hubert ; Opitz, Lennart ; Tan, Ge ; Sieverling, Lina ; Schlapbach, Ralph
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2013-12, Vol.14 (1), p.370-370, Article 370
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A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories
Author / Creator:Agis-Balboa, Roberto Carlos ; Arcos-Diaz, Dario ; Wittnam, Jessica ; Govindarajan, Nambirajan ; Blom, Kim ; Burkhardt, Susanne ; Haladyniak, Ulla ; Agbemenyah, Hope Yao ; Zovoilis, Athanasios ; Salinas-Riester, Gabriella ; Opitz, Lennart ; Sananbenesi, Farahnaz ; Fischer, Andre
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2011-10, Vol.30 (19), p.4071-4083
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Individualized Pooled CRISPR/Cas9 Screenings Identify CDK2 as a Druggable Vulnerability in a Canine Mammary Carcinoma Patient
Author / Creator:Inglebert, Marine ; Dettwiler, Martina ; He, Chang ; Markkanen, Enni ; Opitz, Lennart ; Naguleswaran, Arunasalam ; Rottenberg, Sven
Publisher:Switzerland: MDPI AG
Journal title:Veterinary sciences, 2025-02, Vol.12 (2), p.183
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Impaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-γ
Author / Creator:Lang, Christine ; Hildebrandt, Anke ; Brand, Franziska ; Opitz, Lennart ; Dihazi, Hassan ; Lüder, Carsten G. K.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2012-01, Vol.8 (1), p.e1002483
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Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer
Author / Creator:Kündig, Pascale ; Giesen, Charlotte ; Jackson, Hartland ; Bodenmiller, Bernd ; Papassotirolopus, Bärbel ; Freiberger, Sandra Nicole ; Aquino, Catharine ; Opitz, Lennart ; Varga, Zsuzsanna
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2018-05, Vol.16 (1), p.118-118, Article 118
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Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease
Author / Creator:Montag, Judith ; Hitt, Reiner ; Opitz, Lennart ; Schulz-Schaeffer, Walter J ; Hunsmann, Gerhard ; Motzkus, Dirk
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2009-08, Vol.4 (1), p.36-36, Article 36
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Concurrent Activation of Both Survival-Promoting and Death-Inducing Signaling by Chloroquine in Glioblastoma Stem Cells: Implications for Potential Risks and Benefits of Using Chloroquine as Radiosens...
Author / Creator:Müller, Andreas ; Weyerhäuser, Patrick ; Berte, Nancy ; Jonin, Fitriasari ; Lyubarskyy, Bogdan ; Sprang, Bettina ; Kantelhardt, Sven Rainer ; Salinas, Gabriela ; Opitz, Lennart ; Schulz-Schaeffer, Walter ; Giese, Alf ; Kim, Ella L.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-04, Vol.12 (9), p.1290
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Correction to: Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer
Author / Creator:Kündig, Pascale ; Giesen, Charlotte ; Jackson, Hartland ; Bodenmiller, Bernd ; Papassotirolopus, Bärbel ; Freiberger, Sandra Nicole ; Aquino, Catharine ; Opitz, Lennart ; Varga, Zsuzsanna
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2018-07, Vol.16 (1), p.180-180, Article 180
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Transcriptional Repression of Hox Genes by C. elegans HP1/HPL and H1/HIS-24
Author / Creator:Studencka, Maja ; Wesołowski, Radosław ; Opitz, Lennart ; Salinas-Riester, Gabriela ; Wisniewski, Jacek R. ; Jedrusik-Bode, Monika
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2012-09, Vol.8 (9), p.e1002940-e1002940
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A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells
Author / Creator:Galli, Soledad ; Jahn, Olaf ; Hitt, Reiner ; Hesse, Doerte ; Opitz, Lennart ; Plessmann, Uwe ; Urlaub, Henning ; Poderoso, Juan Jose ; Jares-Erijman, Elizabeth A. ; Jovin, Thomas M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-10, Vol.4 (10), p.e7541-e7541
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Showing 1 to 20 of 46 results

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Long fragments achieve lower base quality in Illumina paired-end sequencing

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Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

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SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis

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A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspring

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SRF and MKL1 Independently Inhibit Brown Adipogenesis

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Impact of RNA degradation on gene expression profiling

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Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring

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Engineered peptide barcodes for in-depth analyses of binding protein libraries

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The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers

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Identification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women

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Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching

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A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories

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Individualized Pooled CRISPR/Cas9 Screenings Identify CDK2 as a Druggable Vulnerability in a Canine Mammary Carcinoma Patient

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Impaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-γ

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Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer

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Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

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Concurrent Activation of Both Survival-Promoting and Death-Inducing Signaling by Chloroquine in Glioblastoma Stem Cells: Implications for Potential Risks and Benefits of Using Chloroquine as Radiosens...

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Correction to: Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer

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Transcriptional Repression of Hox Genes by C. elegans HP1/HPL and H1/HIS-24

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A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells

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