Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
About this item
Full title
Author / Creator
Xiang, Zheng , Ren, Haiyan , Hu, Ying S , Coin, Irene , Wei, Jing , Cang, Hu and Wang, Lei
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
An unnatural amino acid that forms a covalent bond with a proximal cysteine can be introduced into proteins, facilitating a variety of applications.
Natural proteins often rely on the disulfide bond to covalently link side chains. Here we genetically introduce a new type of covalent bond into proteins by enabling an unnatural amino acid to react...
Alternative Titles
Full title
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3882359
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3882359
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.2595
