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The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor gene...

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor gene...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883927

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

About this item

Full title

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2014-04, Vol.33 (17), p.2157-2168

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Many tumor suppressor genes (TSGs) are silenced through synergistic layers of epigenetic regulation including abnormal DNA hypermethylation of promoter CpG islands, repressive chromatin modifications and enhanced nucleosome deposition over transcription start sites. The protein complexes responsible for silencing of many of such TSGs remain to be i...

Alternative Titles

Full title

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883927

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2013.178

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