The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor gene...
The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes
About this item
Full title
Author / Creator
Cai, Y , Geutjes, E-J , de Lint, K , Roepman, P , Bruurs, L , Yu, L-R , Wang, W , van Blijswijk, J , Mohammad, H , de Rink, I , Bernards, R and Baylin, S B
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Many tumor suppressor genes (TSGs) are silenced through synergistic layers of epigenetic regulation including abnormal DNA hypermethylation of promoter CpG islands, repressive chromatin modifications and enhanced nucleosome deposition over transcription start sites. The protein complexes responsible for silencing of many of such TSGs remain to be i...
Alternative Titles
Full title
The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883927
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883927
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2013.178
