A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA...
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia
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Author / Creator
Metzeler, K H , Maharry, K , Kohlschmidt, J , Volinia, S , Mrózek, K , Becker, H , Nicolet, D , Whitman, S P , Mendler, J H , Schwind, S , Eisfeld, A-K , Wu, Y-Z , Powell, B L , Carter, T H , Wetzler, M , Kolitz, J E , Baer, M R , Carroll, A J , Stone, R M , Caligiuri, M A , Marcucci, G and Bloomfield, C D
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Acute myeloid leukemia (AML) is hypothesized to be sustained by self-renewing leukemia stem cells (LSCs). Recently, gene expression signatures (GES) from functionally defined AML LSC populations were reported, and expression of a ‘core enriched’ (CE) GES, representing 44 genes activated in LCSs, conferred shorter survival in cytogenetically normal...
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Full title
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3890747
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3890747
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2013.181
