MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
About this item
Full title
Author / Creator
Steidl, Christian , Shah, Sohrab P. , Woolcock, Bruce W. , Rui, Lixin , Kawahara, Masahiro , Farinha, Pedro , Johnson, Nathalie A. , Zhao, Yongjun , Telenius, Adele , Neriah, Susana Ben , McPherson, Andrew , Meissner, Barbara , Okoye, Ujunwa C. , Diepstra, Arjan , van den Berg, Anke , Sun, Mark , Leung, Gillian , Jones, Steven J. , Connors, Joseph M. , Huntsman, David G. , Savage, Kerry J. , Rimsza, Lisa M. , Horsman, Douglas E. , Staudt, Louis M. , Steidl, Ulrich , Marra, Marco A. and Gascoyne, Randy D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
MHC regulator in cancers
Using whole transcriptome sequencing, Steidl
et al
. identify recurrent gene translocations in B-cell lymphomas that involve the class II transactivator
CIITA
, the 'master regulator' of the major histocompatibility complex. These translocations downregulate cell surface HLA class II and, with some fusion par...
Alternative Titles
Full title
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
Authors, Artists and Contributors
Author / Creator
Shah, Sohrab P.
Woolcock, Bruce W.
Rui, Lixin
Kawahara, Masahiro
Farinha, Pedro
Johnson, Nathalie A.
Zhao, Yongjun
Telenius, Adele
Neriah, Susana Ben
McPherson, Andrew
Meissner, Barbara
Okoye, Ujunwa C.
Diepstra, Arjan
van den Berg, Anke
Sun, Mark
Leung, Gillian
Jones, Steven J.
Connors, Joseph M.
Huntsman, David G.
Savage, Kerry J.
Rimsza, Lisa M.
Horsman, Douglas E.
Staudt, Louis M.
Steidl, Ulrich
Marra, Marco A.
Gascoyne, Randy D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3902849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3902849
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature09754
