Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
About this item
Full title
Author / Creator
Bolli, Niccolo , Avet-Loiseau, Hervé , Wedge, David C. , Van Loo, Peter , Alexandrov, Ludmil B. , Martincorena, Inigo , Dawson, Kevin J. , Iorio, Francesco , Nik-Zainal, Serena , Bignell, Graham R. , Hinton, Jonathan W. , Li, Yilong , Tubio, Jose M.C. , McLaren, Stuart , O' Meara, Sarah , Butler, Adam P. , Teague, Jon W. , Mudie, Laura , Anderson, Elizabeth , Rashid, Naim , Tai, Yu-Tzu , Shammas, Masood A. , Sperling, Adam S. , Fulciniti, Mariateresa , Richardson, Paul G. , Parmigiani, Giovanni , Magrangeas, Florence , Minvielle, Stephane , Moreau, Philippe , Attal, Michel , Facon, Thierry , Futreal, P Andrew , Anderson, Kenneth C. , Campbell, Peter J. and Munshi, Nikhil C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Multiple myeloma is an incurable plasma cell malignancy with a complex and incompletely understood molecular pathogenesis. Here we use whole-exome sequencing, copy-number profiling and cytogenetics to analyse 84 myeloma samples. Most cases have a complex subclonal structure and show clusters of subclonal variants, including subclonal driver mutatio...
Alternative Titles
Full title
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
Authors, Artists and Contributors
Author / Creator
Avet-Loiseau, Hervé
Wedge, David C.
Van Loo, Peter
Alexandrov, Ludmil B.
Martincorena, Inigo
Dawson, Kevin J.
Iorio, Francesco
Nik-Zainal, Serena
Bignell, Graham R.
Hinton, Jonathan W.
Li, Yilong
Tubio, Jose M.C.
McLaren, Stuart
O' Meara, Sarah
Butler, Adam P.
Teague, Jon W.
Mudie, Laura
Anderson, Elizabeth
Rashid, Naim
Tai, Yu-Tzu
Shammas, Masood A.
Sperling, Adam S.
Fulciniti, Mariateresa
Richardson, Paul G.
Parmigiani, Giovanni
Magrangeas, Florence
Minvielle, Stephane
Moreau, Philippe
Attal, Michel
Facon, Thierry
Futreal, P Andrew
Anderson, Kenneth C.
Campbell, Peter J.
Munshi, Nikhil C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3905727
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3905727
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3997
