Therapy of Chronic Myeloid Leukemia: Twilight of the Imatinib Era?
Therapy of Chronic Myeloid Leukemia: Twilight of the Imatinib Era?
About this item
Full title
Author / Creator
Publisher
Egypt: Hindawi Publishing Corporation
Journal title
Language
English
Formats
Publication information
Publisher
Egypt: Hindawi Publishing Corporation
Subjects
More information
Scope and Contents
Contents
Chronic myeloid leukemia (CML) results from the clonal expansion of pluripotent hematopoietic stem cells containing the active BCR/ABL fusion gene produced by a reciprocal translocation of the ABL1 gene to the BCR gene. The BCR/ABL protein displays a constitutive tyrosine kinase activity and confers on leukemic cells growth and proliferation advant...
Alternative Titles
Full title
Therapy of Chronic Myeloid Leukemia: Twilight of the Imatinib Era?
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929284
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929284
Other Identifiers
ISSN
2090-5661,2090-567X
E-ISSN
2090-567X
DOI
10.1155/2014/596483
