Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally a...
Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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A bioorthogonal organometallic reaction is a biocompatible transformation undergone by a synthetic material exclusively through the mediation of a non-biotic metal source; a selective process used to label biomolecules and activate probes in biological environs. Here we report the
in vitro
bioorthogonal generation of 5-fluorouracil from a bio...
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Full title
Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929780
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929780
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4277
