ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48
ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
ORM (yeast)-like protein isoform 3
(
ORMDL3
) has recently been identified as a candidate gene for susceptibility to asthma; however, the mechanisms by which it contributes to asthma pathogenesis are not well understood. Here we demonstrate a functional role for ORMDL3 in eosinophils in the context of allergic inflammation. Eosinophils rec...
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Full title
ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3940275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3940275
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3479
