IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and mi...
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Tissue-specific Langerhans cells and microglia develop
in situ
before birth. Colonna and colleagues identify IL-34 produced by keratinocytes and neurons as the relevant ligand of CSF1R necessary for their generation.
The differentiation of bone marrow–derived progenitor cells into monocytes, tissue macrophages and some dendritic cell (DC)...
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Full title
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3941469
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3941469
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2360
